I think we need to bring this discussion down to some basics and let's start with the evolution of life itself. Key question is what is the origin of membrane bound microbes? Key to that is the evolution of membranes. The approach to answering this question is not biological, but from the field of physics.
We also need to ask how did eukaryotes arise? (See previous post about Lynn Margulis).
The next question is how did multi-cellular organisms arise?
I have attached some reading that will help frame a better understanding of these questions.
There have been a common misconception re: induce antibiotic resistance in bacteria as it relates to evolution. The point is that resistance is not "induced" in bacteria by antibiotics. It is selected. See "Antibitioc Resistance is Ancient" The bottom line is that bacteria have had the genetic capability for 30,000 years to produce the resistance factors to all known classes of antibiotics. Bear in mind that antibiotics are derived from natural products and read Gerry Wrights paper (attached). IMO this does not relate to evolution as a primary driving force.
What I am trying to do here is establish the basic underlying factors (natural laws) that drive evolution of life and am starting with the protobiotic environment from which life evolved. No fossil record for this period. My reasoning is that we need to see evidence that this environment has the necessary factors to form membranes to package the molecular machinery of life, that early unicellular organisms (known to exist from the fossil record) can form muticellular organisms, and that symbiotic relationships between prokaryotes can result in the appearance of the eukaryotes. Establishing the scientific basis for this leads to the next stage of complexity of life.
More later.