Quote:
Originally Posted by GratefulCitizen
Seen the weight thing come up a few times now.
Will share what I've learned.
Step 1: stop consuming poison.
-Do not eat anything containing high fructose corn syrup,
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I have highlighted this from GC's post because, IMO, that is the most important factor contributing to obesity. HFCS alters the gut microbiota in such a way as to promote more efficient caloric conversion of food. Hence, you can actually eat far fewer calories and still gain weight. There is substantial experimental evidence in mice and clinical evidence in humans that this alteration in intestinal microbiota occurs in obese patients. The etiology for that change is still unknown.
MO: HFCS is a stressor to intestinal endothelial cells and the cellular response to the stress is to secrete proteins that alter the composition of the intestinal microbiota. We have experiments planned to test this hypothesis. If correct then the process can be reversed. My advice, stop consuming HFCS and the microbiota reversal will occur naturally. The weight loss will follow and will be maintainable.