Here's a list of completed, ongoing, and recruiting studies on High Altitude from clinicaltrials.gov. Some involve PDE5 inhibitors.
http://clinicaltrials.gov/ct2/result...in+Sickness%22
http://clinicaltrials.gov/ct2/result...de+Sickness%22
http://clinicaltrials.gov/ct2/result...onary+Edema%22
http://clinicaltrials.gov/ct2/result...onary+Edema%22
You can also do a search in PubMed such as these:
http://www.ncbi.nlm.nih.gov/pubmed/17408118
http://www.ncbi.nlm.nih.gov/pubmed/20225909
http://www.biomedsearch.com/nih/Phos.../20225909.html
So looks like a good bit of activity with most if not all results thus far showing good effect of PDE5 inhibitors on attenuating effects of AMS/HAPE/HACE, although one article I saw said that PDE5 inhibitors temporarily worsened AMS and headaches at altitude but helped attenuate HAPE/HACE.
The short of it is - nothing definitive yet, but overall positive results so far.
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Last edited by olhamada; 05-18-2011 at 10:10.
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