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Answer the questions that have been present to you.
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I don't need to discuss firearms. I joined because of the 2006 flu threat; this was & is an excellent resource for the medical & biological issues. Its going off the rails with the political speculation. |
An ELISA antibody test
Is this sort of thing likely to be implementable soon enough to be useful for epidemiology?
preprint: https://www.medrxiv.org/content/10.1....17.20037713v1 A serological assay to detect SARS-CoV-2 seroconversion in humans Fatima Amanat, et al Posted March 18, 2020 doi: https://doi.org/10.1101/2020.03.17.20037713 article about the subject: https://www.sciencemag.org/news/2020...virus-pandemic |
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2) So? Can you document this has happened in this instance? Ad-hominum arguments add nothing of value. |
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But being the highly principled scientist you seem to tout yourself as do you disagree with the Molecular Biologists/virologist/infectious disease types researching viruses they do not yet understand or some countries use of them as a cheap alternative to full scale ground or economic warfare? what you seem to suggest is research done by these types is not of a forward thinking discovery and prevention but of the knee jerk reactionary type....I know a few in the field who scoff at the reactionary accusation not that it does not happen but the constant research and seeking is a continuum as I understand it. So again who is the irresponsible ones creating panic those that are extrapolating data from partial information and telling people that this virus is 10x??? more deadly or those that are looking at a declared enemy of the U.S. and seeing that methodology and timing as suspect? it seems educated people would and could see the economic impact of overreactions by government officials as being far more destructive for people living check by check and those who depend on medications and controlled diets etc......and finally loss of liberty. There are medical sections on this website for those wishing to stay closer to just the science and not the causal factors that enabled this irrational response. But in the general thread we are going to link things together for a broader understanding of what is actually going on. |
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As for your claim the topic going off the rails with speculation. IMO, no one has a handle on how this started. The idea of a intentional release is no more speculative than it was accidental. One thing that is becoming abundantly clear is China lied. |
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I just looked again at the TMC-14 section and there are about 3 posts this year. None anything to do with SARS-COVID-2. I repeat my opinion that the medical and political aspects would be easier to follow in separate threads. |
Article on expedient mask strategies
https://www.medscape.com/viewarticle/927259#vp_1
One hospital is wearing expedient cloth over N95 masks so they can be used longer. References to several past studies on the issue -- they have mixed results. IMO sociologically, goverment should be urging people to wear home made masks starting last week. People are just in denial. |
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Evidence for fecal load 12 days after recovery
My takaway is to avoid breathing the air in public restrooms, and maybe narrow hallways adjacent.
https://www.medscape.com/viewarticle/926856#vp_2 COMMENTARY Fecal Evidence of COVID-19 Raises Transmission Concerns David A. Johnson, MD March 18, 2020 New studies are expanding our understanding of the possible fecal transmission of COVID-19. Assessment by polymerase chain reaction (PCR) has provided evidence of virus in the stool and the oropharynx outside the nasopharynx and respiratory tract. Virus in the stool may be evident on presentation and last throughout the course of illness resolution for up to 12 days after the respiratory virus evidence is gone. When I say "virus evidence," it's because it does not necessarily correspond to infectivity. Studies from fecal transmission to infectivity have yet to be done. However, it's certainly suggestive that the virus is intact, at least as far as how the PCR assay for the respiratory definition is now being applied the same way for stool. Why Possible Fecal Transmission Is Important The Centers for Disease Control and Prevention recommends that after two negative respiratory tests separated by ≥ 24 hours, patients can be dismissed from having transmissibility infection risk for COVID-19. But we now know that these stools may lag up to 12 days after. In fact, in one of the most recent studies looking at 73 patients, approximately 24% remained positive in their stool for evidence of virus, though not necessarily infection, after showing negative in respiratory samples. When we consider other disease states with fecal-oral transmission, the classic example that comes to mind is Clostridium difficile. We tell patients with C difficile–positive stool that when they use and flush the toilet, they can aerosolize these spores, which may then deposit on the surface areas in their bathroom. ... The potential for fecal transmissibility has yet to be defined, but we know from a recent study that the virus has been evident in the stool of just over 50% of patients and remains in nearly 25% otherwise clear of respiratory evidence of virus. |
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I'll edit it a bit. |
They try to estimate mortality by deaths on a given day vs number of cases on the day of infection (in the past). They used 14 days in the past. The number "earlier" in time is over 20%, and decays steadily towards the WHO cumulative mortality rate of 5.6%
So my takaway is that we might see a huge mortality rate pretty soon. Hopefully the government will be ahead of that and explain this sort of curve so its not a surprise. Better yet, if they can demonstrate the upwards curve is leading to that rate. Unless the public changes its behavior. Real estimates of mortality following COVID-19 infection David Baud et al 12MAR20 -- so maybe a bit dated https://www.thelancet.com/journals/l...195-X/fulltext EDIT: a followup post by the guy Mugwump recommended recently touches on the same "convergence" theme: https://medium.com/@tomaspueyo/coron...e-f4d3d9cd99ca SNIP The two ways you can calculate the fatality rate is Deaths/Total Cases and Death/Closed Cases. The first one is likely to be an underestimate, because lots of open cases can still end up in death. The second is an overestimate, because it’s likely that deaths are closed quicker than recoveries. What I did was look at how both evolve over time. Both of these numbers will converge to the same result once all cases are closed, so if you project past trends to the future, you can make a guess on what the final fatality rate will be. This is what you see in the data. China’s fatality rate is now between 3.6% and 6.1%. If you project that in the future, it looks like it converges towards ~3.8%-4%. This is double the current estimate, and 30 times worse than the flu. It is made up of two completely different realities though: Hubei and the rest of China. Hubei’s fatality rate will probably converge towards 4.8%. Meanwhile, for the rest of China, it will likely converge to ~0.9%: SNIP Edit again: see his Chart 12; it matches the high initial death rate of the first article. So - the system gets overwhelmed very very very early. |
ITB, your a nasty fuck. PSM asked you a direct question, and your next post is on fecal matter. That bullshit is not lost on me, nor is your continued passive aggressive attitude. So why are you here?
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Ya’ll leave InTheBlack and others some leeway. These are trying times, patience is wearing thin and emotions running high. Everybody just step back and take a deep breath before posting negative attacks on each other.
And if you can’t take a deep breath call your doctor to report your medical condition to see you too have the virus. |
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