From the CDC
Flu Vaccine
What viruses will the 2020-2021 flu vaccines protect against?
There are many different flu viruses and they are constantly changing. The composition of U.S. flu vaccines is reviewed annually and updated as needed to match circulating flu viruses. Flu vaccines protect against the three or four viruses (depending on the vaccine) that research suggests will be most common.
For 2020-2021, trivalent (three-component) egg-based vaccines are recommended to contain:
A/Guangdong-Maonan/SWL1536/2019 (H1N1)pdm09-like virus (updated)
A/Hong Kong/2671/2019 (H3N2)-like virus (updated)
B/Washington/02/2019 (B/Victoria lineage)-like virus (updated)
Quadrivalent (four-component) egg-based vaccines, which protect against a second lineage of B viruses, are recommended to contain:
the three recommended viruses above, plus B/Phuket/3073/2013-like (Yamagata lineage) virus.
For 2020-2021, cell- or recombinant-based vaccines are recommended to contain:
A/Hawaii/70/2019 (H1N1)pdm09-like virus (updated)
A/Hong Kong/45/2019 (H3N2)-like virus (updated)
B/Washington/02/2019 (B/Victoria lineage)-like virus (updated)
B/Phuket/3073/2013-like (Yamagata lineage) virus
Are there any changes to the 2020-2021 Northern Hemisphere vaccines from what was included in this season’s 2019-2020 U.S. flu vaccines?
Yes, this season’s flu vaccines were updated to better match viruses expected to be circulating in the United States.
The egg-based H1N1 vaccine component was updated from an A/Brisbane/02/2018 (H1N1)pdm09-like virus to an A/Guangdong-Maonan/SWL1536/2019 (H1N1)pdm09-like virus.
The cell- or recombinant-based H1N1 vaccine component was updated from an A/Brisbane/02/2018 (H1N1)pdm09-like virus to an A/Hawaii/70/2019 (H1N1)pdm09-like virus.
The egg-based H3N2 vaccine component was updated from an A/Kansas/14/2017 (H3N2)-like virus to an A/Hong Kong/2671/2019 (H3N2)-like virus.
The cell- or recombinant-based H3N2 vaccine component was updated from an A/Kansas/14/2017 (H3N2)-like virus to an A/Hong Kong/45/2019 (H3N2)-like virus.
The B/Victoria lineage vaccine component was updated from a B/Colorado/06/2017 (B/Victoria lineage)-like virus to a B/Washington/02/2019 (B/Victoria lineage)-like virus.
The B/Yamagata lineage vaccine component was not updated.
Are there any new vaccines licensed for use during the 2020-2021 flu season?
There are two new vaccines licensed for use during the 2020-2021 flu season.
The first is a quadrivalent high-dose vaccine licensed for use in adults 65 years and older. This vaccine will replace the previously licensed trivalent high-dose vaccine.
The second new vaccine that will be available is a quadrivalent adjuvanted vaccine licensed for use in adults 65 years and older.
This vaccine is similar to the previously licensed trivalent vaccine containing MF59 adjuvant, but it has one additional influenza B component.
More information about new vaccines available this year.
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