DNA Test from 23andMe ??

[Paslode]

Originally Posted by Badger52

Nice letter. 'Cause we know the FBI would never misrepresent anything to a judge in order to obtain a warrant.

This is true, and companies never mis-represent or break their own privacy guidelines. I seem to recall many years ago AT&T and others denying they were assisting the .GOV in collecting phone data.

Marketing to general population wise FtDNA is probably on the lower tier of the totem pole, it's just blaaaaah in comparison to AncestryDNA, it's just not fun. So FtDNA must generate income by other means and that might mean partnering with the Feds.

As this DNA collection stuff continues to evolve there is going to be a lot good and bad. A few of the negatives will be government intrusion, DNA based insurance, DNA base reperations and male neutering. One of the major positives could be preventative medicine.

[Badger52]

Originally Posted by Paslode

DNA based insurance... One of the major positives could be preventative medicine.

Possibly to the latter. The former I don't see happening unless the community crying "must cover all pre-existing conditions!" is kicked to the curb, since they won't acknowledge actuarial shit that effects risk/reward decisions.

[Flagg]

Originally Posted by Badger52

Possibly to the latter.

Precision medicine is going to be huuuuge.

But not until there’s a big enough set of anonymised genomes to use as fuel for machine learning to do the grunt work.

2016 saw the $1000 barrier for full genome sequencing(30x coverage to mitigate for sequencing errors) broken by Veritas Genetics.

In late 2018 Veritas Genetics offered full genome sequencing for $199 for the first 1000 people. They sold out in 6 hours.

But even the temporary promotion price of $199 still isn’t anywhere cheap enough.

When full genome sequencing is the price of a pizza + 5-7 years after 10 million people have been sequenced, is when I reckon we start to see breakthroughs in truly understanding genetic resilience, starting with the biggies of cardiovascular disease and colorectal cancer.

CRISPR-like chemical scalpels for genetic splicing has a lot of potential for both good and evil.

I reckon it will be at least 2030 before we see a big enough drop in sequencing cost, a big enough data set, and enough time to crunch and confirm learnings to develop something actionable to start moving the needle.

On a podcast I was listening to recently, I was surprised to learn the amount of data transferred in a single human body in the form of genetic mutation is measured in terabytes per day.

Brave new world, but we are literally just scratching the surface.

[Badger52]

Originally Posted by Flagg

Brave new world, but we are literally just scratching the surface.

All well said above.

I recall a couple of light-years ago when the Genome project was just starting, they were soliciting people who had computers left on during off-hours so they could "time-share" over a fledgling internet to max their CPU operations in a 24 hour period. I did that for awhile - long before any real cyber concerns - and they (apparently) used my little CPU for some stuff at night according to their thank you note. So it's been an ongoing & accelerating, but still long term, thing. But accelerating is the key word there.

The resultant data at times have been used for various agenda, though. And at times wacisss when the results blow the wrong way. I'll be long gone...

[Penn]

We did both the 23andme and ancestry. Both 100% Northern European. Finnish, Irish, 23 and me was far more detailed, but that was dependent on answering all 1700 + research questions. Two values that were interesting: 1, a medical tendency for DVT, which occurred and resulted in a Femoral artery by-pass. If I had taken the test earlier that may not have occurred.
2. Across the three spectrum for cancer, all were negative. Neanderthal Ancestry 244 Variants
You have more Neanderthal variants than 15% of 23andMe customers.

Some of those related in my gene pool, who are Finnish, have in excess 340-400 Neanderthal Ancestry Variants.

[Penn]

Badger52

The resultant data at times have been used for various agenda, though. And at times wacisss when the results blow the wrong way. I'll be long gone...

The collection will result in medical advances with the goal of eliminating conditions that shorten life for those in control. The future belongs to those that can create a population on mindless worker bees, to serve their needs. Matrix's meets central planning on a planetary scale.

[Streck-Fu]

Originally Posted by Penn

Badger52

The collection will result in medical advances with the goal of eliminating conditions that shorten life for those in control. The future belongs to those that can create a population on mindless worker bees, to serve their needs. Matrix's meets central planning on a planetary scale.

I saw this movie, Gattaca.

[tom kelly]

Originally Posted by Penn

Badger52

The collection will result in medical advances with the goal of eliminating conditions that shorten life for those in control. The future belongs to those that can create a population on mindless worker bees, to serve their needs. Matrix's meets central planning on a planetary scale.

Hopefully, it doesn't belong to AI (Artifical Intelligence)