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View Full Version : Inside the DEA: A chemist's quest to identify mystery drugs


frostfire
12-29-2016, 04:02
Reminds me of when spice and bathsalts were popular at Bragg and other bases. Thankfully, at some point joes concluded it's not cool to defecate yourself before jumping off the balcony...
Back then the law could not catch up with all the synthetic pot that was legal simply by changing a chain here and there.

The article brings back (selective) fond memories of my lab rat days with the NMR and spectrometer.

http://bigstory.ap.org/article/85502793452845a092d39ad74c04145f/inside-dea-chemists-quest-identify-mystery-drugs

Emily Dye, a 27-year-old forensic chemist at the Drug Enforcement Administration's Special Testing and Research Laboratory, did not know if anyone had died from taking this powder, or how much it would take to kill you.

What she did know was this: New drugs were appearing in the lab every other week, things never before seen in this unmarked gray building in Sterling, Virginia. Increasingly, these new compounds were synthetic opioids designed to mimic fentanyl, a prescription painkiller up to 50 times stronger than heroin.

This, Dye realized, could be one of them.

The proliferation of rapidly evolving synthetic opioids has become so fierce that the DEA says they now constitute an entire new class of drugs, which are fueling the deadliest addiction crisis the United States has ever seen.

The fentanyl-like drugs are pouring in primarily from China, U.S. officials say — an assertion Beijing maintains has not been substantiated. Laws cannot keep pace with the speed of scientific innovation. As soon as one substance is banned, chemists synthesize slightly different, and technically legal, molecules and sell that substance online, delivery to U.S. doorsteps guaranteed.

More Americans now die of drug overdoses than in car crashes. Almost two-thirds of them, more than 33,000 in 2015 alone, took some form of opioid — either heroin, prescription painkillers or, increasingly, synthetic compounds like U-47700 and furanyl fentanyl, manufactured by nimble chemists to stay one step ahead of the law.

It is now forensic chemists like Dye who are on the front line of the nation's war on drugs, teasing out molecular structures of mystery drugs so they can be named, tracked and regulated.

bblhead672
12-29-2016, 08:42
Reminds me of when spice and bathsalts were popular at Bragg and other bases. Thankfully, at some point joes concluded it's not cool to defecate yourself before jumping off the balcony...
Back then the law could not catch up with all the synthetic pot that was legal simply by changing a chain here and there.

The article brings back (selective) fond memories of my lab rat days with the NMR and spectrometer.

http://bigstory.ap.org/article/85502793452845a092d39ad74c04145f/inside-dea-chemists-quest-identify-mystery-drugs

Emily Dye, a 27-year-old forensic chemist at the Drug Enforcement Administration's Special Testing and Research Laboratory, did not know if anyone had died from taking this powder, or how much it would take to kill you.

What she did know was this: New drugs were appearing in the lab every other week, things never before seen in this unmarked gray building in Sterling, Virginia. Increasingly, these new compounds were synthetic opioids designed to mimic fentanyl, a prescription painkiller up to 50 times stronger than heroin.

This, Dye realized, could be one of them.

The proliferation of rapidly evolving synthetic opioids has become so fierce that the DEA says they now constitute an entire new class of drugs, which are fueling the deadliest addiction crisis the United States has ever seen.

The fentanyl-like drugs are pouring in primarily from China, U.S. officials say — an assertion Beijing maintains has not been substantiated. Laws cannot keep pace with the speed of scientific innovation. As soon as one substance is banned, chemists synthesize slightly different, and technically legal, molecules and sell that substance online, delivery to U.S. doorsteps guaranteed.

More Americans now die of drug overdoses than in car crashes. Almost two-thirds of them, more than 33,000 in 2015 alone, took some form of opioid — either heroin, prescription painkillers or, increasingly, synthetic compounds like U-47700 and furanyl fentanyl, manufactured by nimble chemists to stay one step ahead of the law.

It is now forensic chemists like Dye who are on the front line of the nation's war on drugs, teasing out molecular structures of mystery drugs so they can be named, tracked and regulated.

The government should expend more effort and tax dollars on this than trying to take away the right for citizens to keep and bear arms.

Old Dog New Trick
12-29-2016, 11:48
The government should expend more effort and tax dollars on this than trying to take away the right for citizens to keep and bear arms.

JMO - The government (local and national) should end this "war on drugs" and let stupid go full retard. Stupid is as stupid does! This is a self-correcting problem if people would stop interfering in Darwin's theory of life.

Don't do drugs unless your doctor prescribed them to you.

Calling 911 and giving kids Narcan to save them from poor choices only perpetuates more poor choices.

Again JMO - YMMV

Flagg
12-29-2016, 13:36
http://www.vox.com/science-and-health/2016/12/20/14005776/deaths-pain-drug-opioids-fentanyl-chart

Story(link at bottom) about a horrible topic.

I only wish the real journalists who put this story together had pushed another level to find any correlation between political campaign contributions at the state/federal level as protection for this quasi-legal crack house.

In a world of big data and easy accurate analysis there is simply no way these companies were unaware of the epic growth in addiction their product was fuelling.

Pleading ignorance and blaming physicians/pharmacists does not absolve them of their strategic level duty of care.

They need to be smashed like big tobacco.

A chart correlating the rise of opioid related overdoses/deaths with the massive increases in sales between 2007-2012:

30mg increased 600%(36x increase in active ingredient)

15mg increased 300%(6x increase in active ingredient)

10mg increased nearly 200%(4x increase in active ingredient)

5mg flat

That's a near 50x increase in prescription by active ingredient volume in a 5 year period.

The only difference between these pharma companies and Pablo Escobar is that Pablo didn't have political topcover in the USA.

http://www.wvgazettemail.com/news-he...e-of-overdoses

Unless I'm missing something?